Pharmacotherapy for Gastrointestinal and Hepatobiliary Disorders Essay

Pharmacotherapy for Gastrointestinal and Hepatobiliary Disorders Essay

Pharmacotherapy for Gastrointestinal and Hepatobiliary Disorders Essay

In the case study offered, the patient’s primary symptoms are diarrhea, nausea, and vomiting. The patient also discloses a history of drug usage and a potential hepatitis C infection. The patient’s prescription medication points to a history of hypertension and hypothyroidism. The most likely diagnosis, based on the available subjective data, is Hepatitis C. (Patel & Flamm, 2022). This diagnosis is supported by the patient’s symptoms. As a result, substance abuse is a common risk factor for this illness since patients who inject drugs using needles and syringes might develop it (Teti, 2020). Research has also revealed that untreated hepatitis C can have harmful repercussions on the body, including congestive heart failure and hypothyroidism, as the patient has shown (Terrault, 2019). Nonetheless, an HCV antibody test is necessary to confirm this diagnosis.

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            The diagnosis will determine the patient’s treatment strategy. Direct-acting antiviral (DAA) tablets, such as simeprevir 150 mg orally once daily in conjunction with ribavirin and PEG-IFN, are indicated for 12-week pharmaceutical treatment for the management of hepatitis C. (Heffernan et al., 2019). Nonetheless, loperamide will be used to treat diarrhea, and antiemetics such as ondansetron to treat nausea and vomiting as part of the patient’s symptomatic care at this time (Terrault, 2019). To control the accompanying issues, such as hypothyroidism and hypertension, the patient should keep taking the prescribed medications, such as Synthroid 100mcg, Nifedipine 30mg, and prednisolone 10 mg. Given that the patient has a history of substance use, prompt treatment is required to prevent future consequences such as liver cirrhosis (Paul & Davis, 2018). The patient should be educated on the importance of complying with the treatment plan. Monitoring of the treatment outcome is necessary to promote appropriate alteration of medication for a desirable outcome. The significance of adhering to the treatment plan should be explained to the patient. It is important to keep track of treatment results to modify medicine in a way that will provide the desired results.

References

Heffernan, A., Cooke, G. S., Nayagam, S., Thursz, M., & Hallett, T. B. (2019). Scaling up prevention and treatment towards the elimination of hepatitis C: a global mathematical model. The Lancet, 393(10178), 1319–1329. https://doi.org/10.1016/s0140-6736(18)32277-3

Patel, P., & Flamm, S. (2022). Screening, Diagnosis, and Treatment of Alcohol-Related Liver Disease and Alcohol-Associated Hepatitis. Gastroenterology & Hepatology, 18, 409. https://www.gastroenterologyandhepatology.net/files/2022/06/0722-Patel-Flamm_final-1.pdf

Paul, S., & Davis, A. M. (2018). Diagnosis and Management of Nonalcoholic Fatty Liver Disease. JAMA, 320(23), 2474. https://doi.org/10.1001/jama.2018.17365

Terrault, N. A. (2019). Hepatitis C elimination: challenges with under-diagnosis and under-treatment. F1000Research, 8, 54. https://doi.org/10.12688/f1000research.15892.1

Teti, E. (2020). Hepatitis C management and treatment among people who inject drugs in Italy: an exploratory pilot survey. MISSION, 54. https://doi.org/10.3280/mis54-2020oa9744

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Write a 1-page paper that addresses the following:

• Explain your diagnosis for the patient, including your rationale for the diagnosis.
• Describe an appropriate drug therapy plan based on the patient’s history, diagnosis, and drugs currently prescribed.
• Justify why you would recommend this drug therapy plan for this patient. Be specific and provide examples.

Case Study

Patient HL comes into the clinic with the following symptoms: nausea, vomiting, and diarrhea. The patient has a history of drug abuse and possible Hepatitis C. HL is currently taking the following prescription drugs:

• Synthroid 100 mcg daily
• Nifedipine 30 mg daily
• Prednisone 10 mg daily