What is the pathological process in the development and presentation of eczema versus psoriasis?Discuss the pathological process and presentation of atopic dermatitis and its relationship to asthma and allergies.
Eczema versus Psoriasis
Both psoriasis and eczema are inflammatory diseases, and the main difference between these two disorders is their respective underlying causes. Psoriasis is an autoimmune disorder signifying that it causes dysfunction of the immune system and increases the growth rate of skin cells (Kim et al., 2019). The cells start piling on top of each other, leading to the formation of a white scale. Psoriasis affects about three percent of the world population of people aged 50 years and above (Kim et al., 2019). Psoriasis presents with cycles of sustained remission and inflammation cycles and limited control of keratinocytes.
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Pruritus lesions know eczema with epidermal changes and indefinite borders. The appearance of Eczema lesions can be as papules, erythema, or scales and can be evident in an acute, subacute, chronic stage. In chronic eczema, the patient’s skin would become thick, leathery, and constant irritation and scratch (Kim et al., 2019). The treatment of psoriasis and eczema are more or less the same, with some of the common remedies being over-the-counter relief, topical, phototherapy, and biologics
Pathological Process and Presentation of Atopic Dermatitis and its Relationship to Asthma and Allergies
Despite the scanty information on Atopic Dermatitis (AD), studies have expounded that a combination of ineffective immune control and dysfunction of skin barrier may lead to Atopic Dermatitis’s pathobiology. The epidermis is key as a functional and physical barrier (Chovatiya & Silver, 2019). The proteins that are responsible for epidermal function include keratins, transglutaminases, Filaggrin (FLG), and intercellular proteins. The defects registered on these proteins result in the penetration of allergen and other microbes in the skin. These penetrations are the major causes of asthma and allergies.
References
Chovatiya, R., & Silverberg, J. I. (2019). Pathophysiology of atopic dermatitis and psoriasis: implications for management in children. Children, 6(10), 108. https://doi.org/10.3390/children6100108
Kim, J., Kim, B. E., & Leung, D. Y. (2019, March). Pathophysiology of atopic dermatitis: clinical implications. In Allergy and asthma proceedings (Vol. 40, No. 2, p. 84). OceanSide Publications. https://doi.org/10.2500/aap.2019.40.4202
What is the pathological process in the development and presentation of eczema versus psoriasis?
Discuss the pathological process and presentation of atopic dermatitis and its relationship to asthma and allergies.